Dr. Ashish Gupta has completed his Ph.D. in Biochemistry from the King George’s Medical University. Subsequently, he has gained the expereince as post-doctoral fellow and Research Associate, from The Johns Hopkins University, School of Medicine; Department of Radiology and Cardiology, Baltimore, MD, USA.

Thereafter, Dr. Gupta has joined as an Assistant Professor at Centre of Bio-Medical Research, Lucknow and presentely working over here at the capacity of Additional Professor.    

He has published more than 50 original research articles/book chapters at international repute.

He also got several international awards from various scientific societies. 

He is the reviewer of various peers journals including Circulation, Nature Medicine, Circulation Research, Journal of Proteome Research, PLOS one, JPBA, CCA, etc. 

He is a lifetime member of International Society for Magnetic Resonance in Medicine, California, USA, Nuclear Magnetic Resonance Society, Bangalore, National Academy of Science, Allahabad, and Indian Academy of Biomedical Sciences, India

Fellowships and Honors:

 Ø Junior Research Fellowship (Indian Council of Medical Research, India), 2001-2006.

Ø Senior Research Fellowship (Council for Scientific and Industrial Research, India), 2004-2007.

Ø Student Education Stipend Award from International Society for Magnetic Resonance in Medicine, Miami, Florida, USA, 2005

Ø Student Education Stipend Award from International Society for Magnetic Resonance in Medicine, Seattle, Washington, USA, 2006.

Ø Richard R. Ernst and Kurt Wuthrich Fellowship Award for attending the International Society for Magnetic Resonance in Medicine, Seattle, Washington, USA, 2006.

Ø Student Education Stipend Award from International Society for Magnetic Resonance in Medicine, Stockholm, Sweden, 2010

Ø E. K. Zavoisky stipend Award from International Society for Magnetic Resonance in Medicine, Singapore, 2016

Ø  E. K. Zavoisky stipend Award from International Society for Magnetic Resonance in Medicine, Honolulu, HI, USA 2017

Ø  Best Investigator Award from Asia Pacific Association for the Study of Liver (APASL), Kyoto, Japan 2024    

PhD (supervisor/co-supervisor):

1. Early biomarkers identification of urinary bladder cancer using a comprehensive proteometabolomic approach. (PhD Awarded 2014)

2.   Application of modern analytical techniques in prostate cancer biomarkers investigation. (PhD Awarded 2017)

3. Metabolomic approach for the diagnosis of coronary artery disease-chronic stable angina and unstable angina. (PhD Awarded 2018)

     MCh (Urology):

1. Serum proteomics versus cystoscopy as a tool for follow up of carcinoma bladder: A prospective study. (MCh Awarded 2016)

     N-PDF supervisor:

1. Effect of change in lifestyle on circulating exosomes phenotype and function. National Post-Doctoral fellowship (N-PDF) from Science and Engineering Research Board (SERB), 2017 

• Research Grants Awarded

  Ø  Energy starvation in heart failure: causal role for creatine kinase? Independent postdoctoral fellowship - AHA funded at the Johns Hopkins University, Baltimore, MD, USA. 2010. 

  Ø  Early biomarkers identification of urological cancer in blood samples using proteometabolomics method (Government of India, Ministry of Science & Technology), at Centre of Biomedical Magnetic Resonance, India. 2013 

  Ø  Analogue of prothrombin time: identification and assay development of novel non-invasive and surrogate indicator of blood coagulopathy. ICMR, New Delhi, India, 2021

  Ø  Prostate Cancer: probing of comprehensive (cellular and systemic) metabolomics-based biomarker as a surrogate of the histopathology-based Gleason score grading. ICMR, New Delhi, India, 2021  

More then 50 original research articles have been published in peer reviewed journals at international repute.

Selected publications are as follows:

1.   Gupta A, Chacko VP, Schär M, Akki A, Weiss RG. Impaired ATP kinetics in failing in vivo mouse hearts. Circulation: Cardiovascular Imaging 2011; 4: 42-50. 

2. Gupta A, Akki A, Wang Y, Leppo MK, Chacko VP, Foster DB, Caceres V, Shi Sa, Kirk JA, Su J, Lai S, Paolocci N, Steenbergen C, Gerstenblith G, Weiss RG. Creatine Kinase-mediated improvement of function in failing mouse hearts provides causal evidence the failing heart is energy starved. J Clin Invest 2012; 122: 291-302.

3. Gupta A, Dwivedi M, Mahdii AA, Khetrapal CL, Bhandari M. Broad identification of bacterial type in urinary tract infection using ¹H NMR spectroscopy. J. Proteome Res. 2012; 11: 1844−1854.

4. Kumar D, Gupta A, Mandhani A, Sankhwar SN. Metabolomics derived prostate cancer biomarkers: fact or fiction. J. Proteome Res. 2015; 14: 1455-1464.

5. Ameta K, Gupta A, Ameta D, Sethi R, Kumar D, Ahmad I, Mahdi AA. ¹H NMR-derived metabolomics of filtered serum of myocardial ischemia in unstable angina patients. Clin Chim Acta 2016; 456: 56-62.

6. Kumar D, Gupta A, Nath K. NMR based metabolomics of prostate cancer: A protagonist in clinical diagnostics. Expert Rev. Mol Diagn 2016; 16(6): 651-661. 

7.    Kumar D, Gupta A, Mandhani A, Sankhwar SN. NMR spectroscopy of filtered serum of Prostate cancer: A New frontier in Metabolomics. The Prostate 2016; 76: 1106-1119. [Appeared as a featured article on the spectroscopyNow.com portal Aug 2016]

8.  Ameta K, Gupta A, Kumar S, Sethi R, Kumar D, Mahdi AA. Essential hypertension: A filtered-serum based metabolomics study. Scientific Reports –Nature 2017; 7: 2153-63

9.  Gupta A, Houston B. A comprehensive review of the bioenergetics of fatty acid and glucose metabolism in the healthy and failing heart in non-diabetic condition. Heart Fail Rev 2017; 22: 825-842.

10. Gupta A, Nath K, Bansal N, Kumar M. Role of metabolomics-derived biomarkers to identify Renal Cell Carcinoma: A comprehensive past ten years perspective and advancements. Expert Rev. Mol. Diagn. 2020; 20(1): 5-18.

11. Gupta A, Houston B. Cardiac ¹H MR Spectroscopy: development of the past five decades and future perspectives. Heart Fail Rev 2021; 26: 839-859

12. Singh SP, Sethi R, Saxena SK, Gupta A. Role of metabolomics to identify cardiac hypertrophy: an overview of the past twenty years of development and future perspective. Expert Rev Mol Med 2021; 23: e8

13. Kumar D, Nath K, Lal H, Gupta A. Non-invasive urine metabolomics of prostate cancer and its therapeutic approaches: A current scenario and future perspective. Expert Rev of Proteomics 2021; 18(11): 995-1008

14. Bansal N, Kumar M, Sankhwar SN, Gupta A. Relevance of emerging metabolomics-based biomarkers of prostate cancer: a systematic review. Expert Rev Mol Med 2022; 24: e25

15. Gupta A. Cardiac ³¹P MR spectroscopy: development of the past five decades and future vision; Will it be of diagnostic use in clinics? Heart Fail Rev 2023; 28(2): 485-532.

16. Gupta A, Sarma MS, Kumar A, Meena K, Baishya B, Mathias A, Mishra AK, Rao MK, Singh N, Singh P. Probing and gauging of D-penicillamine xenobiotics in hepatic Wilson disease patients. Biophys Chem 2024; 313: 107306. 

17. Gupta A, Kumar D, Bharti N, Kumar S, Pande S, Agarwal V. Role of noninvasive urinary prothrombin fragment 1+2 to measure blood coagulation indices and dose of acenocoumarol. J. Proteome Res. 2024 (accepted) (IF 5.3) (This article selected for a front cover page to publish as a featured article)

18. Shukla A, Meena K, Gupta A, Sandhir R. 1H NMR-based metabolomic signatures in rodent models of sporadic Alzheimer’s disease and metabolic disorders. ACS Chem Neurosci. 2024; 15(24): 4478-4499. (IF 4.5)